GHRP-6 5mg

GHRP-6 (Growth hormone releasing hexapeptide), a peptide with sequence H(d-W)AW(d-F)K-NH2, is a ghrelin receptor agonist, which has previously been reported to increase gastric emptying in normal rats. A study investigated the prokinetic effect of GHRP-6 in a mouse model of diabetes mellitus have shown that GHRP-6 can accelerate delayed gastric emptying (GE) and intestinal transit (IT), but has no effect on colonic transit (CT) in diabetic mice, which implied that GHRP-6 may exert its prokinetic effects via the cholinergic pathway in the enteric nervous system, and therefore, may have therapeutic potential for diabetic patients with delayed upper gastrointestinal transit.

 

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